The main purpose of this topic is to explore the anatomy and function of some muscle groups, including the gluteal muscles, hamstrings, calf muscles and vastus medialis obliquus. These muscles play a crucial role in providing neuromuscular control of the lower extremity and altered activation patterns of these muscles are a contributing factor for various lower extremity injuries. Muscle strains are the most prevalent type of injury in sports, with the majority affecting the hamstring and calf muscles. There is also a high incidence of recurring strains, which are more serious than the original injury and require a longer absence from training and competition. In spite of the belief in sports medicine that especially muscle injuries are preventable, muscle strain injury and re-injury rates have not improved over the last 30 years. This topic focusses on the training interventions to address the risk factors and exercises that may help to restore proper activation patterns and intermuscular coordination to prevent injuries and enhance performance. This topic also emphasises deceleration mechanics and it’s importance for the prevention of knee injuries. This topic will add some new insights and extend the scope on movement mechanics and efficiency.